To profit from genomics and proteomics, the BioVerdant team has systematically developed automated systems for high throughput enzyme and microbial screening, enzyme discovery, and protein engineering to explore a variety of enzyme-catalyzed reactions. By applying enzymology and process engineering, we significantly expedite the discovery of enzymes with desired substrate specificity. Our technology is well suited to the industrial manufacturing of pharmaceutical, veterinary, and agricultural active ingredients.

Using directed evolution, enzyme mutant libraries can be engineered with higher reactivity and selectivity, greater thermal and solvent stability, and favorable inhibition and pH profiles. A variety of evolution technologies have been developed including site-directed mutagenesis and gene recombination approaches. The engineering efficiency and cost-effectiveness of these methodologies will be dictated by a thorough understanding of the reaction, bioengineering, and a good balance between random screening and rational prediction to create a focused, high-quality enzyme library.